Best CMMS Software for Pharmaceutical Industry

Your Auditor is Coming. Your Maintenance Records Should Be Ready.

Cryotos CMMS eliminates paper PM planners, undocumented breakdowns, and missed calibration schedules - replacing them with a fully digital, 21 CFR-compatible maintenance platform that generates an unbroken, timestamped audit trail from preventive maintenance through to spare part consumption and computer system validation support.

Reduce downtime by 30% with Cryotos Mobile CMMS Software, ensuring efficient operations and increased uptime.
30% Reduction in Downtime
Increase ROI by 275% and maximize returns by deploying Cryotos Mobile CMMS Software.
275% Increase in ROI
Extend asset lifespan by 15% with Cryotos Mobile CMMS Software, ensuring longevity and optimal performance.
15% Increase in Asset Lifespan
Experience a 25% reduction in repair times with Cryotos Mobile CMMS Software.
25% Decrease in Repair Times
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See Why Thousands of Leading Companies Trust
Cryotos Maintenance Software

Accreditation to Cryotos from Software WorldClient Reviews for Cryotos CMMS Software on CapterraAccreditation for Cryotos from Software AdviceAccreditation for Cryotos from G2

Addressing the 5 Critical Problems of Manufacturing Maintenance

In the fast-paced, high-stakes manufacturing world, efficiency, productivity, and reliability are the cornerstones of success. Cryotos Manufacturing Maintenance Software is designed to streamline your operations, reduce downtime, and optimize asset management. Here are the key benefits you can expect when you choose Cryotos:

Reactive Maintenance Is Costing You
Paper PM planners mean missed activities become deviations
Pinnacle Life Sciences confirmed: 'We have a PM planner. We have to review it day by day so we are not missing something. If we have missed something, we have to file a deviation for that.' Every missed PM triggers a formal deviation - a process that consumes hours and creates regulatory exposure.
Compliance Documentation Challenges
No photographic evidence that maintenance was actually performed - not just signed off
Centrient Pharma raised the critical concern: 'Whether gaskets have been replaced or not - old one and new one with documented photographs needs to be attached to it. Otherwise only documented by the operator and not actually done.' This is a GMP data integrity gap that digital-only sign-offs cannot close.
Skilled Labor Shortage and Knowledge Loss
Computer system validation (CSV) is a non-negotiable barrier for pharma software adoption
Pinnacle Life Sciences stated it explicitly: 'My main concern is software validation - in pharma we have to perform Computer System Validation. Because there are audits from USFDA and whatever data we are generating in our plant has to be accepted by the regulatories.' Every new software must pass CSV before it can be used.
Disconnected Systems and Delayed Response
Calibration schedules live in spreadsheets with no automated tracking or compliance calendar
Thyrocare (1,000+ assets, 30 labs, 70 engineers) and Centrient both independently asked: 'Do you manage calibration schedules and a calendar for calibrations?' Calibration non-compliance is a top-five finding in pharma facility inspections.
Lack of Visibility into Asset Performance
6,000 spare line items in SAP with no min/max reorder logic, no mobile issuance, no maintenance-linked consumption
SGD Group confirmed: '6,000 live line items in engineering stores. Some items need min/max levels maintained - can the system auto-generate PRs to SAP when stock falls below minimum?' Manual stock management of critical spares is a production continuity risk.

How Cryotos Solves It?

Three critical jobs that pharmaceutical operations need done - reliably, every day.
JOB 1 OF 3: Eliminate Deviations by Making Every PM Non-Negotiably Documented
Replace paper PM planners, manual sign-offs, and Excel calendars with a fully automated, role-controlled, photographic-evidence-backed maintenance system.
Feature Benefits Outcome
52-week PM calendar with time-based AND usage/meter-based scheduling Map your entire annual preventive maintenance plan once. Set daily, weekly, monthly, bimonthly or half-yearly frequencies. Cryotos auto-generates tickets on the exact scheduled date, assigns them to the right technician, and pushes notifications to their mobile before the activity is due Not a single scheduled PM is missed - because the system raises it automatically. Compliance rate against PM calendar becomes measurable and reportable. Deviation filings for missed activities drop toward zero.
Mandatory before-and-after photo capture with LIVE image enforcement (no gallery uploads) Require technicians to photograph the part before removal and after installation as a mandatory checklist step. The system only accepts live camera captures - no uploading stored images - and timestamps each photograph with the technician's ID The 'signed off but not actually done' gap closes. Every gasket change, every filter replacement, every component swap has irrefutable, timestamped photographic evidence. USFDA auditors see proof, not paper.
Multi-level digital approval workflows with role-based digital signature capture Model your exact sign-off hierarchy: technician submits, supervisor reviews, QA validates, HOD closes. Each step captures a digital signature with timestamp. The checklist does not proceed without each level being completed. Configure any depth of approval chain without coding Approval flows mirror GMP documentation requirements. Any question about who approved what, and when, is answered in one click. The software generates a complete, unalterable activity log ready for any regulatory inspection.
JOB 2 OF 3: Create an Unbroken Digital Thread from Equipment Registration to Disposal
From reactor qualification to calibration scheduling to spare part consumption to asset lifecycle cost - one system, one record, one audit trail.
Feature Benefits Outcome
Asset calibration scheduling with before/after readings, interval tracking and compliance dashboard Register calibration requirements per equipment (pressure gauges, balances, temperature probes, analytical instruments). Define internal vs. external vendor responsibility, set recurrence intervals, and capture before-calibration and after-calibration readings with the responsible person's digital sign-off Calibration overdue status is visible on a dashboard - not discovered during an inspection. A pharmaceutical company managing 1,000+ assets across 30 sites can see calibration compliance status in one view, not thirty spreadsheets.
AI knowledge base trained on maintenance history, manuals, and breakdown records Upload equipment manuals, SOPs, and qualification documentation into the Cryotos knowledge base. The AI is also automatically trained on every work order and breakdown record. Technicians ask questions in plain language from the mobile app and receive contextual answers about previous breakdowns, parts used, and corrective actions New technician induction time shortens. Repeat breakdowns caused by unknown root causes are avoided. For injectable manufacturers where every deviation has regulatory weight, AI-assisted diagnosis reduces incorrect interventions.
MTTR, MTBF, OEE and downtime dashboards with machine aging and cost trend analysis For each asset, Cryotos automatically calculates MTTR, MTBF, availability, and OEE based on actual maintenance data. Total cost of ownership (parts + labour + additional) is tracked per asset over its entire lifecycle. AI surfaces patterns indicating a machine is aging and approaching replacement threshold Engineering heads and CTOs gain evidence-based justification for capital equipment replacement rather than debating with finance from memory. The data required for equipment qualification decisions is captured automatically, not compiled manually.
JOB 3 OF 3:  Connect Engineering Stores to SAP with Real-Time Spare Part Consumption Traceability
Bi-directional SAP HANA integration means every spare part movement - from MOQ alert to PR to PO to GRN to maintenance ticket - is reconciled automatically.
Feature Benefits Outcome
Bi-directional SAP HANA integration: stock movements sync in real time When a spare part is issued in Cryotos to a maintenance work order, the deduction is automatically pushed to SAP. When an inward GRN is posted in SAP, the quantity is updated in Cryotos. Both systems stay in sync without manual double-entry. Proven live at TVS Motors and Jockey India Engineering stores teams stop maintaining parallel spreadsheets alongside SAP. The 6,000 line-item store becomes manageable from mobile, with instant stock visibility per bin. SAP remains the financial ledger while Cryotos drives the operational workflow.
QR-coded spare parts with mobile issuance, min/max MOQ alerts, and auto PR generation Every spare in the warehouse gets a unique QR code. Technicians scan the QR to issue against a work order from their phone - no handwritten storeroom chits. When quantity falls below MOQ, Cryotos raises an automatic alert and can generate a purchase request directly linked to the preferred supplier Critical spares are never discovered to be out-of-stock during an urgent breakdown. For sterile manufacturing and API plants where maintenance-related production stops carry batch discard risk, proactive stock management directly protects manufacturing output.
Spare part consumption linked to maintenance ticket with part history by asset When a technician replaces a component, he scans the spare, enters quantity consumed, and the system records which work order that part was used for, on which asset, by which technician, on what date. This data feeds directly into the asset's maintenance cost history For every auditor question - 'What parts were used on this reactor in the past 18 months?' or 'Show me the gasket replacement history for Line 3 filling machine' - the answer is generated in one report, not assembled from multiple logs.

Addressing Pharma's Non-Negotiable Compliance Requirements

Cryotos is built for the reality of regulated pharmaceutical environments. Here is how we address the specific concerns raised by pharma maintenance leaders.

Reactive Maintenance Is Costing You
Computer System Validation (CSV) Support
Cryotos provides the documentation, test evidence, and IQ/OQ/PQ support needed to complete a Computer System Validation (CSV) for regulatory submissions. We are audit-ready and will participate in your validation exercise directly.
Compliance Documentation Challenges
21 CFR Part 11 - Ready Data Integrity Controls
Role-based access prevents unauthorised data modification. Every entry is timestamped and attributed to a named user with audit trail logging. Individual user licenses - not concurrent users - ensure traceability to a single accountable person for every record.
Skilled Labor Shortage and Knowledge Loss
Separate Tenant Architecture on AWS
Each pharma client's data is stored in a completely isolated tenant on Amazon Web Services. No shared infrastructure with other organizations. On-premise deployment options available for sites with strict data sovereignty or network security requirements.
Disconnected Systems and Delayed Response
RFID / Barcode / NFC Asset Tracking
For pharmaceutical manufacturers who need to locate assets by RFID tag (including motors, portable equipment, and tools), Cryotos supports RFID, NFC, and barcode-based tracking. Map view and location tracking available for tagged assets.
Lack of Visibility into Asset Performance
Centralised GMP Document Repository
Upload SOPs, qualification documents, equipment manuals, calibration certificates, and maintenance procedures. Attach documents to specific assets. Technicians access them on mobile during the maintenance activity. Role-controlled viewing and downloading.
Lack of Visibility into Asset Performance
AMC, Certificate & Compliance Expiry Automation
Map every AMC contract, equipment certificate, and compliance document against assets or locations. Set advance notification windows. Automated email alerts are sent to the responsible person on the defined number of days before expiry - never discovered during an audit.
Cryotos mobile app offers real-time updates, detailed reports, and intuitive navigation for efficient maintenance operations.

Mobile Maintenance Management: Empowering Your Technicians

Cryotos' mobile CMMS app is designed for industrial environments, supporting both iOS and Android devices. Technicians can:
  • Receive real-time work orders

  • Access maintenance procedures and asset history

  • Scan QR codes for instant asset data

  • Track parts inventory and place orders directly

  • Close tasks with digital signatures

Offline Mode ensures your team can work without interruptions, syncing data when back online.

From Implementation to Audit-Ready in One Deployment

Cryotos understands that pharma implementations require more than software setup. Our team handles the full digitalization program.

Reactive Maintenance Is Costing You
PM Checklist Digitisation
Share your existing paper PM checklists and SOPs. Our team converts them into configured digital workflows with the exact input types, mandatory fields, and approval chains your procedures require - before go-live.
Compliance Documentation Challenges
Asset & Calibration Data Bulk Upload
Provide your equipment register. Cryotos supports bulk upload of all assets, sub-assets, calibration schedules, spare part lists, and vendor information. No manual data entry by your team.
Skilled Labor Shortage and Knowledge Loss
SAP / ERP Integration Setup
Our technical team conducts a detailed integration scoping session with your IT and SAP team. REST API-based bi-directional integration is configured to match your data flows before cutover.
Disconnected Systems and Delayed Response
CSV Documentation Support
Cryotos participates in your Computer System Validation process - providing system documentation, supporting IQ/OQ/PQ test execution, and generating the evidence required for regulatory submission.

Make Your Next USFDA Audit Your Easiest One

We will digitise your PM checklists, calibration schedules, and spare part register before your pilot begins.

Start Your Free Trail Today
Implementation

The Cryotos Preventive Maintenance software is easy to implement and use thanks to its user-friendly design. Plus, our customer support team is always available to answer any questions. We also provide end-to-end implementation support and training so that you can get the most value from your investment in the Cryotos PM software.

Implementation Support Provided by Cryotos Team
Training

The Cryotos CMMS software team is dedicated to providing high-quality training so that you can easily learn the software. We offer both online and in-person training so that you can learn at your own pace. Our team is always available to answer any questions you may have. In addition, we have videos that can help you get instant access to resources when you need them.

Cryotos offers online and in-person training, videos, and support to help you master CMMS software at your own pace.
APIs

Cryotos offers an open REST API interface with proper authentication that simplifies the process of integrating and exchanging data across ERP & third applications. This API enables different software programs, like (SAP, Salesforce, and PeopleSoft.) to interact with CMMS Systems without hiccups, allowing efficient data sharing across multiple platforms.

API Services Offered
Support

At Cryotos, we understand that our customers may need support at any time of day or night. That's why we have a team of experts available 24/7 to help them with whatever they need. We're dedicated to providing the best possible service and always putting our customers first.

Cryotos offers 24/7 expert support to assist customers anytime, ensuring top-notch service and priority care.

Frequently Asked Question about Cryotos Manufacturing Maintenance Software

Case Studies: Chronicles of Success with Cryotos

Testimonial Image
How did Planys Technologies Overcome Manual Documentation and Missing Key Details in Work Orders?

Explore how Planys have encountered, 96% availability and reliability rate for assets, 25% reduction in critical breakdowns, and Enhanced operational efficiency after implementig Cryotos CMMS Software!

Testimonial Image
How Alzain Farms LLC Enhanced Maintenance Efficiency with Cryotos CMMS?

Alzain Farms LLC faced challenges with inefficient maintenance tracking, frequent equipment breakdowns, and manual processes. Explore how the firm overcome these issues and digitized their maintenance operations for real-time tracking and proactive scheduling.

Our Other Maintenance Solutions

Dive into the world of streamlined maintenance management with our suite of Cryotos CMMS solutions.
Designed to cater to a wide range of maintenance needs, our offerings are tailored to enhance operational efficiency.
CMMS software, one of the maintenance solution of Cryotos

CMMS Software

Enhance maintenance efficiency by managing assets, scheduling tasks, and tracking work orders seamlessly.
Cryotos maintenance management software

Maintenance Management Software

Streamline your maintenance workflows, enabling managers to plan, schedule, and track maintenance activities efficiently.
Asset management software

Asset Maintenance Management Software

Make data-driven decisions and optimize asset utilization by tracking asset history, maintenance schedules, and performance metrics.
Facility management software, Cryotos maintenance application

Facility Management Software

From space planning to maintenance scheduling and vendor management, FMS helps facility managers ensure that buildings are safe, functional, and efficient.
Field service management software

Field Service Management Software

Optimize field operations by efficiently scheduling, dispatching, and tracking service tasks in real-time.
PTW software

Permit-to-Work Software

Streamline the permit process, ensuring safe, compliant, and efficient management of high-risk tasks.

Don't Take Our Words!
Here From Our Esteemed Clients!

Gurit, supplier for composite materials, engineering services and equipment for the wind turbine | Client of Cryotos
Mr. Mohanmurali R

I recently purchased Cryotos CMMS Software for asset management needs at my organization and after a few months of testing and monitoring, I'm incredibly pleased with the results. The software is user friendly, accessible and the design is very intuitive. It covers all the aspects of managing maintenance and repair, starting from preventive maintenance and standardizing operation cycles, to scheduling and streamlining workflows. I am highly satisfied with the performance and the range of features offered by Cryotos. Highly recommendable!

Read Review in G2
Al Zain Poultry Farms LLC, leader in poultry industry offering 100% halal and hygienically packed - Client of Cryotos
Mr. Vishnu S Nair

Since we've started using Cryotos, our team has been able to stay on top of all the various SOPs. Checklists and safety procedures are now easily accessible to everyone, and we can quickly reference them whenever we need to. The software has definitely helped to improve our team's communication and efficiency. Plus, the fact that it's cloud-based means we can access it from anywhere, which is a big plus. It has been a great help in keeping everyone on the same page and up to date with the latest procedures.

Ardelisys, security system installation service - Client of Cryotos
Mr. Sathyendran R.

I am using this application right now for my service team, very good, user friendly, have lot of customisation in workflow and service reports. the team supported for initial implementation, They have good support team. Myself fully recommended this application.

Read Complete Review in G2

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